Spadaro is an Italian surname. This is an occupational surname for a professional soldier or, more specifically, a swordsman.

Notable people with the surname include:

Antonio Spadaro (born 1966), Italian Jesuit priest Carlos Spadaro (19021985), Argentine football attacker Jack Spadaro (born 1948), American mining engineer Micco Spadaro, artistic name of Domenico Gargiulo (16091610 ca. 1675), Italian painter of the Baroque period Odoardo Spadaro (18931965), Italian singer-songwriter and actor Pedro Spadaro (born 1977), Peruvian lawyer Peppino Spadaro (18981950), Italian actor; brother of Umberto Spadaro Umberto Spadaro (19041981), Italian film actor; brother of Peppino Spadaro Other

Spadaro Airport, privately owned, public use airport in Suffolk County, New York, United States