Mahnke is a surname. Notable people with the surname include:
Aaron Mahnke, American podcaster Claudia Mahnke, German mezzo-soprano Dietrich Mahnke (1884–1939), German philosopher and historian of mathematics Doug Mahnke, American comic book artist and penciller
See also Mahnke House, a historical residential building located in Des Moines, Iowa, United States Mahnke Peak, a mountain in Mendocino County, California, United States