Etiocholanolone glucuronide (ETIO-G) is an endogenous, naturally occurring metabolite of testosterone. It is formed in the liver from etiocholanolone by UDP-glucuronyltransferases. ETIO-G has much higher water solubility than etiocholanolone and is eventually excreted in the urine via the kidneys. Along with androsterone glucuronide, it is one of the major inactive metabolites of testosterone.
Formation A glucuronosyltransferase anzyme converts etiocholanolone to its glucuronide by adding a sugar acid to its hydroxy group, with uridine diphosphate (UDP) as byproduct:
See also 3α,5β-Androstanediol 5β-Dihydrotestosterone Androstanediol glucuronide
References
External links Metabocard for Etiocholanolone Glucuronide (HMDB04484) - Human Metabolome Database