La Isla (Spanish for The Island) may refer to:
La isla (film) or The Island, a 1979 Argentine film Isla de Yáquil or La Isla, a town in Chile La Isla (Rengo), a village and a former subdelegation in Rengo commune, Chile La Isla (wetland), Bogotá, Colombia La Isla (Colunga), a civil parish in Asturias, Spain La isla: desafío extremo, an American reality television series La Isla (telenovela), a Puerto Rican telenovela