Dr. Jean Chapman House is a historic home located at Cape Girardeau, Missouri. Designed by John L.E. Boardman and built in 1963, the home is a one-story, V-shaped dwelling with Wrightian style influences. It is built on a steeply sloped lot and is constructed almost entirely of local Ste. Genevieve limestone.

It was listed on the National Register of Historic Places in 2015.

As of 2025, it remains a private residence. https://www.redfin.com/MO/Cape-Girardeau/1150-N-Henderson-Ave-63701/home/130834273?msockid=2718a1415ee06c1f027fb5065fe26dca

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