Mhlongo is a South African surname. It may refer to:
Benson Mhlongo (born 1980), South African football (soccer) player Brighton Mhlongo (born 1991), South African football (soccer) player Busi Mhlongo (1947–2010), South African virtuoso singer, dancer and composer Joseph Mhlongo (born 1990), South African football midfielder Mpumelelo Mhlongo (born 1994), South African sprint and long jump athlete Ndaba Mhlongo (1933–1989), South African actor and choreographer Niq Mhlongo (born 1973), South African journalist and novelist Nombulelo Mhlongo (born 1992), South African actress, classical singer, teacher, and writer Nqobile Mhlongo, South African politician Somizi Mhlongo (born 1972), South African media personality, television presenter, actor, choreographer and socialite Tsepo Mhlongo, South African politician