NCSE may refer to:

Education National Center for Science Education, United States, promotes the teaching of evolutionary biology and climate science National Council for Special Education, Ireland, supports students with disabilities National Certificate of Secondary Education, Trinidad and Tobago, a school qualification

Other Cognistat, formerly known as the Neurobehavioral Cognitive Status Examination (NCSE), a cognitive screening test National Council for Science and the Environment, United States, a business-research alliance for environmental policy Selenocyanate ion NCSe−