Michael Barnes or Mike Barnes may refer to:

Politicians Michael Barnes (British politician) (1932–2018), British Labour MP Michael Barnes (North Carolina politician) (born 1970/1971), acting mayor of Charlotte, North Carolina Michael D. Barnes (born 1943), lawyer and former U.S. Representative from Maryland

Sportspeople Mike Barnes (American football) (born 1950), American football player Michael Barnes (cricketer) (born 1985), English cricketer Michael Barnes (footballer) (born 1988), English footballer Michael Barnes (judoka) (born 1973), American judoka Michael Barnes (motorcyclist) (born 1968), American motorcycle racer

Characters Mike Barnes (Karate Kid), fictional character from the 1989 movie The Karate Kid Part III, and Cobra Kai, Season 5 Mike Barnes (Hollyoaks), a fictional character on British soap opera, Hollyoaks

Others Michael Barnes (arts administrator) (1932–2008), director of the Belfast Festival at Queens and the Grand Opera House, Belfast Michael Barnes (musician), lead singer of Christian rock band RED