System Two, System II or System 2 may refer to:
Computing Acorn System 2, the early microcomputer Apple System 2, the operating system version for the Apple Macintosh Capcom System 2, an arcade system board in the 1990s Cromemco System Two, a computer system by Cromemco from 1978 Channel F System II, game console by Fairchild Digital Access Signalling System 2, the protocol by British Telecom Global File System 2, the file system by Red Hat Master System II, the 8-bit video game console by Sega Namco System 2, the arcade system board by Namco Sega System 2, an arcade system board in the 1990s S2 (programming language), style system 2
Cognition System 1 and System 2 as hypothesized regarding cognition: see Thinking, Fast and Slow
Entertainment: games, music, etc System 2 in Trilogy, an album from rock band Angeldust Super System 2, the poker system System Shock 2, the computer game
See also Operating System/2 by IBM Personal System/2 by IBM