Masucci is a surname. Notable people with the surname include:

Agostino Masucci (c. 1691–1758), Italian painter Alexander "Alex" Masucci (born 1949), American music executive, producer, songwriter and promoter Gaetano Masucci (born 1984), Italian football player Giulia Masucci Fava (1858–?), Italian painter Jerry Masucci (1934–1997), American businessman Matias Masucci, Italian-born American actor and film director Oliver Masucci (born 1968), German actor

See also Masuccio