The 2016 Charlottesville Men's Pro Challenger was a professional tennis tournament played on indoor hard courts. It was the eighth edition of the tournament which was part of the 2016 ATP Challenger Tour, taking place in Charlottesville, United States from October 31 to November 6, 2016.

Singles main-draw entrants Seeds Country Player Rank1 SeedFrances Tiafoe1021Jared Donaldson1092Bjorn Fratangelo1103Denis Kudla1314Tim Smyczek1335Henri Laaksonen1346Peter Polansky 1487Dennis Novikov 1578 1 Rankings are as of October 24, 2016.

Other entrants The following players received wildcards into the singles main draw: Mackenzie McDonald Alexander Ritschard Ryan Shane Carl Söderlund

The following players received entry from the qualifying draw: JC Aragone Yuki Bhambri Gonzales Austin Thai-Son Kwiatkowski

Champions Singles

Reilly Opelka def. Ruben Bemelmans, 6–4, 2–6, 7–6(7–5).

Doubles

Brian Baker / Sam Groth def. Brydan Klein / Ruan Roelofse, 6–3, 6–3.

References