The Copacá River () is a river of Amazonas, Brazil. It is a right tributary of the Uarini River.

The Copacá River defines the eastern boundary of the Baixo Juruá Extractive Reserve, created in 2001. The Copacá is a wide river that lies within the eastern limit of the reserve. The floating litter banks of the river are home to a variety of allochthonous insectivore species of fish, particularly of the genera Microglanis and Phenacorhamdia.

See also List of rivers of Amazonas (Brazilian state)

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