Gananoque is a town in Ontario, Canada.

It can also refer to the following items related to the town: Gananoque River, a river with its mouth at the town of Gananoque Gananoque Lake, a lake of eastern Ontario, Canada Gananoque Islanders, a Canadian Junior "C" ice hockey based in Gananoque Gananoque Airport Gananoque railway station Gananoque & Rideau Railway, historic railway also known as Thousand Islands Railway

Ships named after the town Gananoque (ship), a clipper ship of 1857 HMCS Gananoque (J259), Bangor-class minesweeper, a Canadian warship