Paetsch is a surname. Notable people with the surname include:
Günther Johannes Paetsch (1929–1997), cellist Hans Paetsch (1909–2002), German actor Jessica Rose Paetsch (born 1993), American pair skater Johann Sebastian Paetsch (born 1964), American cellist Julie Paetsch (born 1988), Canadian hockey and football player Michaela Paetsch (1961-2023), American violinist Nathan Paetsch (born 1983), Canadian ice hockey player Otto Paetsch (1909–1945), Standartenführer (Colonel) in the Waffen SS Priscilla Paetsch (1931-2017), American violinist and composer