Dubois Creek is a stream in Franklin County in the U.S. state of Missouri. It is a tributary to the Missouri River.

The headwaters arise at and the confluence with the Missouri is at . The stream source area is along the east side of Missouri Route A between Union and Krakow. The stream flows northeast passing under Route 47 and then north passing under Route 100 to enter the Missouri floodplain just east of Washington.Missouri Atlas & Gazetteer, DeLorme, 1998, First edition, p. 40

Dubois Creek most likely was named after Louis Dubois, an early French frontiersman.

See also List of rivers of Missouri

References