Mike is an unincorporated community in Chariton County, in the U.S. state of Missouri.

The community is on Missouri Route 5 approximately midway between Keytesville to the south and Marceline in adjacent Linn County to the north.Missouri Atlas & Gazetteer, DeLorme, 1st ed., 1998, pp. 22 and 29

History A post office called Mike was established in 1890, and remained in operation until 1906. The community most likely has the name of a resident.

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