Cane Creek is a stream in Cape Girardeau County, Missouri. It is a tributary of Byrd Creek.Burfordville, MO, 7.5 Minute Topographic Quadrangle, USGS, 1980
The stream headwaters arise at along the west side of Fruitland. The stream flows to the southwest passing under I-55 and then Missouri Route 34 west of JacksonJackson, MO, 7.5 Minute Topographic Quadrangle, USGS, 1966 (1978 rev.) to its confluence with Byrd Creek 2.5 miles southeast of Burfordville at .
Cane Creek was lined with cane, hence the name.
See also List of rivers of Missouri
References