Jagannath Ganguly (1921–2007) was an Indian biochemist known for his researches on Vitamin A and fatty acids, which assisted in the better understanding of their metabolism in humans. Born on the 1 April 1921, he authored a book, Biochemistry of Vitamin A, which details the physiological, biochemical and nutritional characteristics of the organic compound. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 1963, for his contributions to biological sciences. He died on 12 December 2007.
Shanti Swarup Bhatnagar Prize for Science and Technology
Prof Jagannath Ganguly was awarded the prestigious Shanti Swarup Bhatnagar Prize for Science and Technology for the year 1963. The award Citation reads: Dr Ganguly is internationally known for his work on the metabolism of vitamin A, biosynthesis of fatty acids and intestinal absorption of lipids. Details: http://ssbprize.gov.in/Content/Detail.aspx?AID=457
Indian National Science Academy
Deceased Fellow http://insaindia.res.in/detail/N68-0252
Biographical Memoirs https://insaindia.res.in/BM/BM33_0812.pdf
Bibliography
Books: Extract from Indian National Science Academy "Biographical Memoirs"
1972 - Edited the book: "Current Trends in the Biochemistry of Lipids", Academic Press, London. 1989 - Authored the book: “Biochemistry of vitamin A”, J. Ganguly, C. R. C. Press Inc., Boca Raton, FL., U.S.A.
Publications and Reviews: Extract from Indian National Science Academy "Biographical Memoirs"
1947
Heat treatment and the biological value of soybean protein: S. S. De and J. Ganguly, Nature, 159, 341.
The intestine as a possible seat of conversion of carotene to vitamin A in the rat and the pig: S. Y. Thompson, J. Ganguly and S. K. Kon, Brit. J. Nutrit., 1, v.
The form of vitamin A in cow's milk: J. Ganguly, S. K. Kon and S. Y. Thompson, Brit. J. Nutrit., 1, III.
1949
The intestinal conversion of carotene to vitamin A: S. Y. Thompson, R. Braude, A. T. Cowic, J. Ganguly and S. K. Kon, Biochem. J. 44, ix.
The conversion of β-carotene to vitamin A in the intestine: S. Y. Thompson, J. Ganguly and S. K. Kon, Brit. J. Nutrit., 3, 58–78.
1950
Further studies on the conversion of β-carotene to vitamin A in the intestine: S. Y. Thompson, R. Braude, M. E. Coats, A. T. Cowie, J. Ganguly and S. K. Kon (1950), Brit. J. Nutrit., 4, 398–421.
1951
Stereoisomerization of the polycis compounds, pro-γ-carotene and prolycopene in chickens and hens: H. J. Deuel Jr., J. Ganguly, B. K. Koe and L. Zechmeister, Arch. Biochem. Biophys., 33, 143–149.
1952
Stereochemical configuration and provitamin A activity: X. A comparison of synthetic 15, 15'-monocis-β-carotene (central monocis-β-carotene) with all-trans-β-carotene in the rat and chick: L. Zechmeister, H. J. Deuel Jr., H. H. Inhoffen, J. Leemann, S. M. Greenberg and J. Ganguly, Arch. Biochem. Biophys., 36, 80–88.
Stereochemical configuration and provitamin A activity: XI. A comparison of synthetic all-trans and dicis-16, 16’-homo-β–carotene C42H58 with all-trans-β–carotene in the rat: H. J. Deuel Jr., H. H. Inhoffen, J. Ganguly, L. Wallcave and L. Zechmeister, Arch. Biochem. Biophys., 40, 352–357.
Studies on the distribution of vitamin A as ester and alcohol and of carotenoids in the plasma proteins of several species: J. Ganguly, N. I. Krinsky, J. W. Mehl and K. J. Deuel Jr., Arch. Biochem, Biophys., 38, 275–282.
1953
Intracellular distribution of vitamin a asterase activity in the rat liver: J. Ganguly and H. J. Deuel Jr., Nature, 172, 120.
Absence of relationship between vitamin A alcohol levels in plasma and in liver of rats: J. Ganguly and N. I. Krinsky, Biochem. J. 54, 177–187.
Studies on vitamin A esterase. III. The intracellular distribution of vitamin A esterase and cholesterol esterase in chicken liver: S. Krishnamurthy, P. Seshadri Sastry and J. Ganguly, Arch. Biochem. Biophys., 75, 6–14.
Provitamin A activity of a structural isomer of cryptozanthin and its methyl ether: H. J. Deuel Jr., J. Ganguly, L. Wallcave and L. Zechmeister, Arch. Biochem. Biophys., 47, 237–240.
Studies on carotenoid metabolism: XII. The effect of dietary carotenoids on the carotenoid distribution in the tissues of chickens: J. Ganguly, J. W. Mehl and H. J. Deuel Jr., J. Nutrit., 50, 73–83.
Studies on carotenoid metabolism: XIII. The carotenoid composition of the blood, liver and ovaries of the rat, ewe, cow and frog: J. Ganguly, J. N. Mehl and H. J. Deuel Jr., J. Nutrit., 50, 73–83.
Studies on carotenoid metabolism. XIV. The biological activity of Echinenone: J. Ganguly, N. I. Krinsky, J. H. Pinckard and H. J. Deuel. Jr., Hoppe-Seyler's Z. Physiol. Chem., 295, 61–66.
Intracellular distribution of vitamin A ester and vitamin A alcohol in rat liver: N. I. Krinsky and J. Ganguly, J. Biol. Chem. 202, 227–232.
1954
Intracellular distribution of vitamin A esterase activity in rat liver: J. Ganguly, Arch. Biochem. Biophys., 52., 186–189.
1955
The site of conversion of provitamin A to vitamin A: J. Ganguly (1955), Silver Jubilee Souvenir, Society of Biological Chemists, India, pp. 195–198
1956
Isolation and nature of Echinenone, a provitamin A: J. Ganguly, N. I. Krinsky and J. H. Pinckard, Arch. Biochem. Biophys., 60, 354–351.
Effect of blocking the reticulo-endothelial system on the storage of vitamin A ester and alcohol in the liver of the rat: S. Krishnamurthy and J. Ganguly, Nature, 177, 575–576.
1957
Studies on vitamin A esterase: I. The general properties and possible specificity of the rat-liver enzyme: P. Seshadri Sastry, S. Krishnamurthy and J. Ganguly, Indian J. Med. Res. 45., 263–272.
Studies on vitamin A esterase: II. The hydrolysis of natural vitamin A esters within the living animal: S. Krishnamurthy, P. Seshadri Sastry and J. Ganguly, Indian J. Med. Res., 45, 391–394.
1958
Association of vitamin A ester and vitamin A alcohol with proteins in rat liver: S. Krishnamurthy, S. Mahadevan and J. Ganguly, J. Biol. Chem., 233, 32–36.
1959
Storage of vitamin A ester, vitamin A alcohol and of carotenoids in association with proteins in chicken liver: S. Mahadevan, S. Krishnamurthy and J. Ganguly, Indian J. Med. Res., 47, 199–206.
The transport of carotenoids, vitamin A and cholesterol across the intestine of rats and chickens: J. Ganguly, S. Krishnamurthy and S. Mahadevan, Biochem. J. 71, 756–762.
The mode of absorption of vitamin A across the intestine of rats: S. Mahadevan, S. Krishnamurthy and J. Ganguly, Arch. Biochem. Biophys., 83, 371–375.
On the mechanism of fatty acid synthesis: Salih J. Wakil and J. Ganguly, J. Am. Chem. Soc., 81, 2597. The mechanism of biosynthesis of higher fatty acids: S. J. Wakil and J. Ganguly, Federation Proc., 18, 346.
1960
Absorption, transport and storage of vitamin A: J. Ganguly, Vitamins and Hormones, Academic Press, New York, 18, 387–402.
Studies on the mechanism of fatty acid synthesis: VII: Biosynthesis of fatty acids from malonyl-CoA: J. Ganguly, Biochem. Biophys. Acta., 40, 110–118.
1961
High cholesterol diet and esterification of cholesterol by the intestinal mucosa of rats: S. K. Murthy, S. Mahadevan and J. Ganguly, Arch. Biochem. Biophys., 95, 176–180.
Fatty acid specificity for the etherification of vitamin A and cholesterol by intestinal and pancreatic enzymes in rats: S. K. Murthy, S. Mahadevan, P. Seshadri Sastry and J. Ganguly, Nature, 189, 482–484.
Studies on vitamin A esterase: IV. The hydrolysis and synthesis of vitamin A esters by rat intestinal mucosae: S. Mahadevan, S. K. Murthy, S. Krishnamurthy and J. Ganguly, Biochem. J., 79, 416–424.
Studies on vitamin A esterase: V. A comparative study of vitamin A esterase and cholesterol esterase of rat and chicken liver: P. Seshadri Sastry and J. Ganguly, Biochem. J., 80, 397–406.
Further studies on the absorption of vitamin A: S. Mahadevan and J. Ganguly, Biochem. J., 81, 53–58.
Fatty acid components of vitamin A ester of sheep liver: K. Subba Rao, P. Seshadri Sastry and J. Ganguly, Arch. Biochem. Biophys., 95, 285–289.
Amino acid patterns in vitamin A deficient rates: P. Malathi, P. Seshadri Sastry and J. Ganguly, Nature, 189, 660–661.
1962
Vitamin C status of vitamin A-deficient rats: P. Seshadri Sastry P. Malathi, K. Subba Rao and J. Ganguly, Nature, 193, 1080–1081.
Enzymic oxidation of vitamin A aldehyde to vitamin A acid by rat liver: S. Mahadevan, S. K. Murthy and J. Ganguly, Biochem. J., 85, 326–331. Studies on cholesterol esterases of the small intestine and pancreas of rats: S. K. Murthy and J. Ganguly, Biochem. J., 83, 460–469. 1963 Some observations on the mechanism of absorption of cholesterol in rats: S. K. Murthy, J. S. K. David and J. Ganguly, Biochem. Biophys. Acta., 70, 490–492.
Biosynthesis of fatty acids: J. Ganguly, Advances in Biochemistry (Publishers: Indian Institute of Science) p. 92-105.
Studies on metabolism of vitamin A: 1. The biological activity of vitamin A acid in rats: P. Malathi, P. Seshadri Sastry K. Subba Rao and J. Ganguly, Biochem. J., 87, 305–311.
Studies on metabolism of vitamin A: 2. Enzymic synthesis and hydrolysis of phenolic sulphates in vitamin A deficient rats: K. Subba Rao, P. Seshadri Sastry and J. Ganguly, Biochem. J., 87, 313–317.
Studies on metabolism of vitamin A: 3. The mode of absorption of vitamin A esters in living rats: S. Mahadevan, P. Seshadri Sastry and J. Ganguly, Biochem. J., 88, 531–534.
Studies on metabolism of vitamin A: 4. The mode of absorption of vitamin A by rat intestine in vitro: S. Mahadevan, P. Seshadri Sastry and J. Ganguly, Biochem. J., 88, 534–539.
1964
Mechanism of absorption of cholesterol and vitamin A in rats: J. Ganguly and S. K. Murthy, LIPID TRANSPORT: (Publishers: Charles Thomas, Springfield, Ill., U.S.A), proceedings of the ‘International Symposium on Lipid Transport, Vanderbilt University, Nashville (Tenn.), U.S.A.: 22–32.
The effect of dietary protein contents on the intestinal conversion of B carotene to vitamin A in rats: D. S. Deshmukh and J. Ganguly, Indian J. Biochem., 1, 204–207.
Studies on metabolism of vitamin A: 5. Dietary protein content and metabolism of vitamin A: D. S. Deshmukh, P. Malathi and J. Ganguly, Biochem. J., 90, 98–104.
Studies on metabolism of vitamin A: 6. The effect of vitamin A deficiency on the activation of sulphate and its transfer to p-nitrophenol in rat liver: K. Subba Rao and J. Ganguly, Biochem. J., 90, 104–109.
Studies on metabolism of vitamin A: 7. Lowered synthesis of ascorbic acid in vitamin A deficient rats: P. Malathi and J. Ganguly, Biochem. J., 92, 521–527.
Studies on metabolism of vitamin A: 8. Effect of ascorbate on isoprenoid metabolism in vitamin A-deficient rats: P. Malathi and J. Ganguly, Biochem. J., 92, 527–531.
Effect of vitamin A deficiency on the concentrations of sodium and potassium in the blood plasma of rats: H. S. Juneja, S. K. Murthy and J. Ganguly, Biochem. J., 93, 499–503.
The fate of intracardially administered retinyl esters in the rat: S. Mahadevan, D. S. Deshmukh and J. Ganguly, Biochem. J., 93, 499–503
Effect of retinoic acid on the reproductive performances of male and female rats: H. S. Juneja, S. K. Murthy and J. Ganguly, Indian J. Exp. Biol., 2, 153–154.
Absorption of retinoic acid (vitamin A acid) in rats: D. S. Deshmukh, P. Malathi, K. Subba Rao and J. Ganguly, Indian J. Biochem., 1, 164–166.
1965
Studies on metabolism of vitamin A: Absorption of retinal (vitamin A aldehyde) in rats: D. S. Deshmukh, S. K. Murthy, S. Mahadevan and J. Ganguly, Biochem. J., 96, 377–382.
Rapid conversion of retinal (vitamin A aldehyde) to retinoic acid (vitamin A acid) in the living rat: D. S. Deshmukh, P. Malathi and J. Ganguly, Biochem. Biophys. Acta., 187, 120–122.