Fedele is both an Italian surname and a masculine Italian given name. Notable people with this name include:
People with the surname Adriano Fedele (born 1947), Italian football player and manager Cassandra Fedele (died 1558), Italian scholar Ivan Fedele (born 1953), Italian composer Joe Fedele, American businessman Matteo Fedele (born 1992), Swiss footballer Michael Fedele (born 1955), American politician Pietro Fedele (1873–1943), Italian historian and politician
People with the given name Fedele Fenaroli (1730–1818), Italian composer Fedele Fischetti (1732–1792), Italian painter Fedele de Giorgis (1887–1964), Italian general