Kharin (masculine, ) or Kharina (feminine, ) is a Russian surname.

This surname is shared by the following people:

Kharin Dmitri Kharine (born 1968), Russian former professional footballer turned goalkeeping coach Mikhail Kharin (born 1976), Russian professional football coach and a former player Pavel Kharin (1927–2023), Soviet-Russian sprint canoer Sergei Kharin (born 1963), Russian professional ice hockey player Vladimir Kharin (footballer) (born 1964), Russian professional football player Vladimir Kharin (zoologist) (1957–2013), Russian zoologist, ichthyologist, herpetologist Yevgeni Kharin (born 1995), Russian professional football player

Kharina Eudoxia Nikolaevna Kharina, mother of Nikolai Kulikovsky (1881–1958), the second husband of Grand Duchess Olga Alexandrovna of Russia, the sister of Tsar Nicholas II of Russia