Muccioli is an Italian surname. Notable people with the surname include:
Anna Maria Muccioli (born 1964), Sammarinese politician Claudio Muccioli (born 1958), Sammarinese politician Dalia Muccioli (born 1993), Italian cyclist Giulio Muccioli (born 1978), pharmacologist and bioanalyst Riccardo Muccioli (born 1974), Sammarinese footballer Simona Muccioli (born 1984), Sammarinese swimmer