Pettis is a surname. Notable people with the name include:
Anthony Pettis (born 1987), American mixed martial artist Austin Pettis (born 1989), American football wide receiver Bill Pettis (born 1942-2016), American competitive bodybuilder Billy James Pettis (1913–1979), American mathematician Bre Pettis (born 1972/1973), American entrepreneur, video blogger and multi-artist Bridget Pettis (born 1971), American basketball player Dante Pettis (born 1995), American football player Dianne Ruth Pettis (1955–2008), New Zealand novelist and journalist Fontaine H. Pettis (~1799?–1858), American slave catcher, fraudster Garret Pettis (born 1989), American soccer player Gary Pettis (born 1958), American baseball player Jerry Pettis (1916–1975), American politician Jill Pettis (born 1952), New Zealand politician Madison Pettis (born 1998), American actress and model Mark Pettis (born 1950), American politician from Wisconsin Michael Pettis (born 1958), American economist Pierce Pettis (born 1954), American singer-songwriter Sergio Pettis (born 1993), American mixed martial artist, brother of Anthony Shirley Neil Pettis (1924–2016), U.S. Representative from California, wife of Jerry Solomon Newton Pettis (1827–1900), American politician Spencer Darwin Pettis (1802–1831), U.S. Representative from Missouri Will Pettis (born 1977), Arena football wide receiver, defensive back