Cozzolino is an Italian surname. Notable people with the surname include:
Andrea Cozzolino (born 1962), Italian politician Dominic Cozzolino (born 1994), Canadian ice sledge hockey player Giuseppe Cozzolino (born 1985), Italian footballer Kei Cozzolino (born 1987), Japanese-born Italian racing driver Pasquale Cozzolino (born 1977), a Neapolitan chef based in New York
See also Leandro Cuzzolino (born 1987), Argentine futsal player