Unrein is a surname. Some notable persons with the name include:

Martin Unrein (1901–1972), a general of the German Army during World War II Mitch Unrein, (born 1987), an American football player Scott Unrein (born 1976), an American composer and is producer/host (since March 2006) of the blog and podcast NonPop Sergio Unrein (born 1991), an Argentine footballer Terry Unrein (born 1962), American former football player

See also Unrein, the fifth studio album by the German band Oomph!