Piacenti is an Italian surname. Notable people with the surname include:

Alessandro Piacenti (born 1992), Italian footballer Erin Piacenti, victim of the 2026 Times Square stabbing attack Gesualdo Piacenti (born 1954), Italian footballer Kirsten Aschengreen Piacenti (1929-2021), Danish art historian and museum director Melchiorre Piacenti (born 1966), Italian footballer