The James M. Amoss Building (also known as the Knights of Pythias Building) is a historic commercial building located at 110 Wabash Street in Wabash, Indiana.

Description and history It was constructed in 1880, and is a two-story, three bay wide, Italianate-style brick building with a limestone foundation and quoins. It features a pressed metal dentil cornice and windows framed by limestone pilasters with simple Tuscan order capitals. Note: This includes and Accompanying photographs

It was listed on the National Register of Historic Places on August 30, 1984. It is located in the Downtown Wabash Historic District.

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