Luers is a surname, mostly found in the United States. Notable people with the surname include:

Jeff Luers (born 1951), American political activist John Luers (1819–1871), American Roman Catholic Church bishop Renee Luers-Gillispie, American college softball player and coach Wendy Luers, American political activist William Luers (1929–2025), American diplomat and museum executive

See also Luer, people with this surname Charles Luers Nordsiek (1896–1937), an American seaman in the United States Navy Bishop Luers High School, a Roman Catholic school in Fort Wayne, Indiana