Bagayoko is a surname. Notable people with the surname include:
Amadou Bagayoko (born 1954), from musical duo Amadou & Mariam Bally Bagayoko (born 1973), French politician Bassala Bagayoko (born 2006), Malian basketball player Fatoumata Bagayoko (born 1988), Malian women's basketball player Mamadou Bagayoko (born 1979), Malian international footballer Mamadou Bagayoko (born 1989), Ivorian footballer Oumar Bagayoko (born 1975), Malian footballer Sekou Bagayoko (born 1987), Malian professional footballer Siaka Bagayoko (born 1998), Malian footballer Tiécoro Bagayoko (1937–1987), Former Director of the National Security Service and General Police of Mali