Rosena may refer to:

Rosena, California the original name of the city of Fontana, California Rosena, Virginia, an unincorporated community in Albemarle County, Virginia, United States Rosena Allin-Khan (born c. 1976), English medical doctor, Labour Member of Parliament (MP) for Tooting since June 2016 Rosena Brown (born ), Irish actress from Belfast, and intelligence officer for the Provisional IRA