Paterlini is an Italian surname. Notable people with the surname include:

Ermes Paterlini (born 1947), Italian footballer Lucas Paterlini (born 1982), Argentine cricketer Matias Paterlini (born 1977), Argentine cricketer Thierry Paterlini (born 1975), Swiss ice hockey player

See also Patrizia Paterlini-Bréchot, Italian biologist