Tsankov () is a Bulgarian masculine surname, its feminine counterpart is Tsankova. Notable people with the surname include:
Aleksandar Tsankov (1879–1959), Bulgarian politician Antoaneta Tsankova (born 2011), Bulgarian rhythmic gymnast Antonio Tsankov (born 1990), Bulgarian football player Asen Tsankov (1912–1994), Bulgarian tennis player and alpine skier Bobi Tsankov (1979–2019), Bulgarian journalist, crime writer and radio personality Dragan Tsankov (1828–1911), Bulgarian politician Ivan Tsankov (born 1984), Bulgarian football player Petko Tsankov (born 1995), Bulgarian football player Tsvetomir Tsankov (born 1984), Bulgarian football goalkeeper