Karamarko is a Serbo-Croatian surname, a patronymic derived from the nickname Karamarko (from kara, "black", and masculine given name Marko). Notable people with the surname include:
Marin Karamarko (born 1998), Croatian footballer Marko Karamarko (born 1993), German footballer Tomislav Karamarko (born 1959), Croatian politician
See also Kara-Marko Vasić, Serbian revolutionary