Spir or SPIR may refer to:
Spir, recently discovered class of actin nucleators in actin remodeling Afrikan Aleksandrovich Spir (1837–1890), Russian philosopher Juan Carlos Spir (1990) Colombian tennis player Spir (album), an album by Karl Seglem's Sogn-A-Song Spir (imprint), an imprint of VDM Publishing that publishes and sells Wikipedia articles in printed form via print on demand Il spir, a viewing platform in the canton of Graubünden in Switzerland Spectral presaturation with inversion recovery, a sequence of magnetic resonance imaging
Acronyms Serviciul de Poliție pentru Intervenție Rapidă, a Romanian rapid response police unit Special Purpose Islamic Regiment, a Chechen organization Standard Portable Intermediate Representation, an intermediate language for parallel compute and graphics by Khronos Group