William Bruce may refer to:
Law and politics William Bruce (diplomat) (died 1610), Scottish diplomat in Poland William Bruce (Canadian politician) (died 1838) William Wallace Bruce (1846–1907), British politician William Cabell Bruce (1860–1946), United States Senator
Others William Bruce of Symbister (died 1624), Scottish landowner Sir William Bruce (architect) (c. 1630–1710), Scottish architect William Bruce, 8th Earl of Kincardine (died 1740), Scottish nobleman William Bruce (minister, born 1757) (1757–1841), Irish Presbyterian educator William Bruce (minister, born 1790) (1790–1868), Irish Presbyterian professor Sir William Bruce, 9th Baronet (1825–1906), Scottish cricketer William George Bruce (1856–1949), American publisher and civic leader William Napier Bruce (1858–1936), British educationalist William Blair Bruce (1859–1906), Canadian painter William Bruce (cricketer) (1864–1925), Australian cricketer William Speirs Bruce (1867–1921), Scottish naturalist and oceanographer William Bruce (VC) (1890–1914), Scottish military officer William J. Bruce III (born 1980), Canadian celebrity publicist
See also Bill Bruce (disambiguation)