Polukhin () is a Russian masculine surname, its feminine counterpart is Polukhina. It may refer to Alexander Polukhin (born 1988), Russian ice hockey player Nikolay Polukhin (born 1982), Russian Paralympic cross-country skier and biathlete Valentina Polukhina (1936–2022), British-Russian scholar Vladimir Polukhin (1932–2009), Russian scientist and engineer