Gospodinov () is a Bulgarian masculine surname, its feminine counterpart is Gospodinova. It may refer to:
Anatoli Gospodinov (born 1994), Bulgarian football goalkeeper Bistra Gospodinova (born 1966), Bulgarian swimmer Georgi Gospodinov (born 1968), Bulgarian poet, writer and playwright Hristo Gospodinov (born 1979), Bulgarian football midfielder Kiril Gospodinov (1934–2003), Bulgarian theater and film actor Marian Gospodinov (born 1974), Bulgarian football player Stanimir Gospodinov (born 1975), Bulgarian football defender Valentina Gospodinova (born 1987), Bulgarian football striker Vanya Gospodinova (born 1958), Bulgarian middle-distance runner Vasil Gospodinov (born 1993), Bulgarian weightlifter Yordan Gospodinov (born 1978), Bulgarian football goalkeeper Zhivko Gospodinov (1957–2015), Bulgarian football player