388th may refer to:

388th Electronic Warfare Squadron, United States Air Force unit located at Eglin Air Force Base, Florida 388th Fighter Squadron or 132nd Fighter Wing (132d W), United States Air Force unit assigned to the Iowa Air National Guard, located at Des Moines International Airport, Iowa 388th Fighter Wing, 4th Fighter Squadron (4 FS), conducts flying operations and equipment maintenance to maintain combat readiness of an 18-aircraft F-16C LANTIRN squadron 388th Operations Group, the flying component of the 388th Fighter Wing, assigned to the Air Combat Command Twelfth Air Force

See also 388 (number) 388, the year 388 (CCCLXXXVIII) of the Julian calendar 388 BC