McQuillen is a surname of Irish origin and related to the similar family names McQuilken, McQuillan, McQuiller and McQuilling. Notable people with the surname include:
Bob McQuillen (1923–2014), American musician and composer Glenn McQuillen (1915–1989), American professional baseball player Kathleen E. McQuillen (born 1955), American, Pioneer of Open Heart Surgery Detroit Michigan See also McQuillan