Uhle is a surname. Notable people with the surname include:
Claudia Uhle (born 1976), German singer George Uhle (1898–1985), American Major League Baseball pitcher Johann Paul Uhle (1827–1861), German physician and pathologist Karl Uhle (1887–1969), German football player Max Uhle (1856–1944), German archaeologist Wolfgang Uhle (1512–1594), German Lutheran priest
See also Ule, a German surname Colegio Max Uhle, German international school in Arequipa, Peru