The following is a list of squads for all sixteen national teams that competed at the Copa América Centenario. Each national team had to submit a squad of 23 players, three of whom had to be goalkeepers. The provisional squads were announced on May 4, 2016. A final selection was provided to the organizers on May 20, 2016.

Group A

Colombia Head coach: José Pékerman

The following 23 players were called up for the final squad. Óscar Murillo withdrew due to injury and was replaced by Yerry Mina.

Costa Rica Head coach: Óscar Ramírez

The following 23 players were called up for the final squad. Goalkeeper Esteban Alvarado was ruled out due to injury on May 20, being replaced by Leonel Moreira. On May 31, Keylor Navas pulled out due to a tendinitis on his left foot and was replaced by Danny Carvajal, and Ariel Rodríguez pulled out due to injury and was replaced by Johnny Woodly.

Paraguay Head coach: Ramón Díaz

The following players were named for the final squad. Forward Roque Santa Cruz was in the initial squad but withdrew injured and was replaced by Antonio Sanabria. Pablo Aguilar and Néstor Ortigoza also pulled out due to injury and were replaced by Víctor Ayala and Iván Piris respectively.

United States Head coach: Jürgen Klinsmann

The final squad was announced on May 21. Timothy Chandler was ruled out due to injury and replaced by Edgar Castillo on May 27.

Group B

Brazil Head coach: Dunga

The following players were named to the final squad. Neymar was unable to participate due to an agreement between his club FC Barcelona and the Brazilian Football Confederation, and was replaced by Lucas Lima. Ricardo Oliveira and Douglas Costa were ruled out due to injury and replaced by Jonas and Kaká on May 20 and 26 respectively. Gabriel Jesus, who would later be part of the 2016 Brazil Olympic squad, was considered as a replacement for Douglas Costa but missed selection through the lack of a U.S. visa. Rafinha and Ederson also pulled out on May 31 and were replaced by Lucas Moura and Marcelo Grohe. In turn, Kaká pulled out due to injury on June 1 and was replaced by Ganso. Luiz Gustavo withdrew from the squad on June 2 for personal reasons and was replaced by Walace.

Ecuador Head coach: Gustavo Quinteros

The following 23 players were called up for the final squad.

Haiti Head coach: Patrice Neveu

The following 23 players were called up for the final squad.https://www.facebook.com/plugins/post.php?href=https%3A%2F%2Fwww.facebook.com%2Fpermalink.php%3Fstory_fbid%3D10153637600331188%26id%3D102815076187&width=500

Peru Head coach: Ricardo Gareca

The following 23 players were called up for the final squad.

Group C

Jamaica Head coach: Winfried Schäfer

The following 23 players were selected for the final squad. Simon Dawkins was ruled out due to injury and replaced by Joel Grant on June 2.

Mexico Head coach: Juan Carlos Osorio

The following 23 players were called up for the final squad. Jürgen Damm withdrew due to injury and was replaced by Cándido Ramírez.

Uruguay Head coach: Óscar Tabárez

The following 23 players were selected for the final squad. On May 30, Cristian Rodríguez pulled out due to injury and was replaced by Diego Laxalt.

Venezuela Head coach: Rafael Dudamel

The following 23 players were selected for the final squad.

Group D

Argentina Head coach: Gerardo Martino

The following 23 players were selected for the final squad.

Bolivia Head coach: Julio César Baldivieso

The following 23 players were called up for the final squad. Samuel Galindo withdrew due to injury and was replaced by Carmelo Algarañaz.El jugador de Petrolero del Chaco reemplazará a Samuel Galindo que fue descartado de la Verde por lesión. Nelson Cabrera was subsequently found to be ineligible by FIFA after the tournament.

Chile Head coach: Juan Antonio Pizzi

The following 23 players were called up for the final squad. On June 1, Matías Fernández pulled out due to injury and was replaced by Mark González.

Panama Head coach: Hernán Darío Gómez

The following 23 players were called up for the final squad.

Player representation

By age Players Oldest: Justo Villar () Youngest: Christian Pulisic ()

Goalkeepers Oldest: Justo Villar () Youngest: Wuilker Faríñez ()

Captains Oldest: Justo Villar () Youngest: James Rodríguez ()

By club Clubs are ordered alphabetically: first by country, then by club name.

Players Clubs6 Atlético Nacional Universitario5 Bolívar Paris Saint-Germain América Atlético Madrid Barcelona4 Oriente Petrolero The Strongest Universidad Católica Saprissa Emelec Atlas Monterrey UANL Juan Aurich Sporting Cristal Porto San Jose Earthquakes3 Independiente Jorge Wilstermann Atlético Mineiro Grêmio São Paulo Vancouver Whitecaps FC Universidad de Chile Santa Fe Alajuelense Herediano Arsenal Everton Manchester United Fiorentina Inter Milan Pachuca Toluca PSV Eindhoven San Francisco Cerro Porteño Olimpia Benfica Celta Vigo Málaga Sporting Kansas City2 Boca Juniors Lanús Racing River Plate Corinthians Santos Colo-Colo LDU Quito Aston Villa Manchester City Middlesbrough Reading Watford West Bromwich Albion Nantes Bayer Leverkusen Milan Torino Portmore United Cruz Azul Querétaro Santos Laguna Tijuana Alianza Lima Deportivo Municipal Espanyol Real Madrid Nacional D.C. United Jacksonville Armada Portland Timbers Seattle Sounders FC Deportivo Táchira 1 Atlético Uruguay Estudiantes Godoy Cruz San Lorenzo Charleroi Standard Liège Petrolero Sport Boys Flamengo Internacional Sport Recife Vasco da Gama Montreal Impact Toronto FC Huachipato Beijing Guoan Hebei China Fortune Shandong Luneng América de Cali Deportivo Cali Independiente Medellín Junior La Equidad Carmelita Cartaginés RNK Split Brøndby Midtjylland Barcelona SC El Nacional Independiente del Valle Bournemouth Birmingham City Blackburn Rovers Chelsea Crystal Palace Hull City Leicester City Leyton Orient Liverpool Stoke City Sunderland Swansea City Tottenham Hotspur West Ham United IFK Mariehamn Bordeaux Caen Cholet Evian Laval Marseille Monaco Nice Paris Saint-Germain B Reims Bayern Munich Borussia Dortmund Borussia Mönchengladbach MSV Duisburg Hertha BSC 1899 Hoffenheim FC Ingolstadt Union Berlin Aigle Noir Platense Ferencváros Mohun Bagan Persepolis Ironi Kiryat Shmona Atalanta Bologna Genoa Juventus Lazio Napoli Cavalier Harbour View Humble Lions Montego Bay United Kazma Chiapas Guadalajara UNAM Zacatecas AZ Feyenoord Jong PSV NEC Molde Sarpsborg 08 Árabe Unido Sporting San Miguelito Tauro Universidad César Vallejo Wisła Kraków Chrobry Głogów Arouca Sporting CP Vila Real Voluntari Rostov Zenit Saint Petersburg Heart of Midlothian Atlético Malagueño Deportivo La Coruña Getafe Huesca Real Sociedad Sevilla Sporting Gijón Tenerife Valencia IFK Göteborg Malmö FF Aarau 1461 Trabzon Galatasaray Kasımpaşa Dynamo Kyiv Carolina RailHawks Colorado Rapids FC Dallas Fort Lauderdale Strikers Houston Dynamo LA Galaxy Minnesota United FC New England Revolution New York Cosmos New York Red Bulls New York City FC Orlando City SC Philadelphia Union Real Salt Lake Saint Louis FC Atlético Venezuela Carabobo Caracas Deportivo La Guaira Mineros de Guayana Zamora Saigon

By club nationality Nations in bold are represented by their national teams in the tournament Players Clubs36 Mexico35 England30 Spain29 United States19 Peru18 Bolivia17 France15 Argentina Italy14 Brazil Colombia12 Costa Rica11 Germany10 Chile Ecuador Portugal8 Venezuela7 Netherlands6 Jamaica Panama Paraguay5 Canada3 China Turkey2 Belgium Denmark Norway Poland Russia Sweden Uruguay1 Croatia Finland Haiti Honduras Hungary India Iran Israel Kuwait Romania Scotland Switzerland Ukraine Vietnam

References