Madruga is a surname of Portuguese origin. Notable people with the surname include:
Alberto Madruga da Costa (born 1940), Azorean politician Djan Madruga (born 1958), Brazilian former swimmer Ivanna Madruga (born 1961), Argentine former tennis player Núria Madruga (born 1980), Portuguese actress and model Pedro Madruga (c. 1430 – 1486), Count of Caminha Roger Madruga (born 1964), Brazilian former swimmer Teresa Madruga (born 1953), Portuguese actress
Fiction Don Ramón, character from the Mexican sitcom El Chavo del Ocho known in Brazil and Portugal as Seu Madruga
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