Five spot may refer to:
Five Spot Café, a jazz club in New York City. Eremalche rotundifolia (desert five spot), a flowering plant in the mallow family Nemophila maculata (fivespot), a flowering plant in the borage family
See also Coccinellidae, a family of small beetles, including five spot ladybird Glyphidocera lactiflosella, the five-spotted glyphidocera moth 5 (disambiguation) Spot (disambiguation)