Helmholtz most commonly refers to Hermann von Helmholtz (1821-1894), German physician and physicist.

Helmholtz or Helmholz may also refer to:

Places named after the German physicist: Helmholtz (lunar crater) Helmholtz (Martian crater) Helmholtz Association of German Research Centres A. Carl Helmholz (1915–2003), an American nuclear physicist Anna von Helmholtz (1834–1899), German salonnière, writer and translator Lindsay Helmholz (1909–1993), an American chemist Helmholtz Watson, a character in Aldous Huxley's Brave New World Helmholtz equation, the eigenvalue problem for the Laplacian operator Helmholtz free energy, a thermodynamic potential measuring obtainable work from a closed system Helmholtz machine, a category of artificial neural networks