Mandler is a surname. Notable people with the surname include:
Albert Mandler (1929–1973), Israeli general Anthony Mandler (born 1973), American music video director George Mandler (1924–2016), American psychologist James Mandler (1922–2007), American basketball player Jean Matter Mandler (born 1929), American psychologist Peter Mandler (born 1958), British historian and academic Walter Mandler (1922–2005), lens designer