Siege of Tbilisi (654) may refer to:

Siege of Tbilisi (627–628), successful siege of the city by the Byzantines and Turks Siege of Tbilisi (1122), successful siege of the city of Tbilisi, capital of the Emirate of Tbilisi, by the Georgians under King David IV Siege of Tbilisi (1386), successful Timurid attack on the capital of Kingdom of Georgia Siege of Tbilisi (1476), part of Turkoman invasions of Georgia Siege of Tbilisi (1795), in 1795, part of Persian invasion of Kingdom of Kartli-Kakheti Siege of Tbilisi (1921), see List of Georgian battles