Mandelli is an Italian surname. Notable people with the surname include:
Davide Mandelli (born 1977), Italian footballer Louis Mandelli (1833–1880), Italian zoologist and ornithologist Mariuccia Mandelli (1925–2015), Italian fashion designer and businesswoman Paolo Mandelli (born 1967), Italian footballer and manager
See also
Mandelli Sistemi Mandelli's mouse-eared bat, species of vesper bat