Roff may refer to:

Computing roff (software), a 1970s typesetting markup language

Places in the United States Roff, Kentucky Roff, Oklahoma

People Derek Roff (born 1930), Australian ranger at Uluṟu-Kata Tjuṯa National Park Derek Roff (born 1949), Canadian biologist Don Roff (born 1966), American writer and filmmaker Jeremy Roff (born 1983), Australian middle-distance runner Joe Roff (born 1975), Australian rugby union player Rosie Roff (born 1989), British ring girl and model

See also Roffe (disambiguation) ROF (disambiguation) Ruff (disambiguation)