Antonio de Zayas (died 16 October 1582) was a Roman Catholic prelate who served as Bishop of Nicaragua (1575–1582). (in Latin)

Biography De Zayas was from Ecija, Spain, and ordained a priest in the Order of Friars Minor. On 19 January 1575, he was appointed during the papacy of Pope Gregory XIII as Bishop of Nicaragua and arrived in Nicaragua in January 1576. Suffering from ill health, he resigned as Bishop of Nicaragua on 8 March 1582 and died on 16 October 1582.

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External links and additional sources (for Chronology of Bishops) (for Chronology of Bishops)