The Lachnospiraceae are a family of obligately anaerobic, variably spore-forming bacteria in the order Eubacteriales that ferment diverse plant polysaccharides to short-chain fatty acids (butyrate, acetate) and alcohols (ethanol). These bacteria are among the most abundant taxa in the rumen and the human gut microbiota.UniProt Members of this family may protect against colon cancer in humans by producing butyric acid. Lachnospiraceae have been found to contribute to diabetes in genetically susceptible (ob/ob) germ-free mice.
Phylogeny The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN) and National Center for Biotechnology Information (NCBI)
16S rRNA based LTP_10_2024 120 marker proteins based GTDB 09-RS220 Unassinged genera: "Africanella" Alou, Fournier & Raoult 2016 non Vermeij & Houart, 1999 Anaerolentibacter Yan et al. 2024 Anaerotaenia Ueki et al. 2016 Chakrabartyella Pardesi et al. 2023 "Ca. Colinaster" Gilroy et al. 2022 "Ca. Darwinimomas" Gilroy et al. 2022 "Ca. Epulonipiscioides" Ngugi et al. 2017 corrig. Oren et al. 2020 "Ca. Equihabitans" Gilroy et al. 2022 Fusibacillus Bai et al. 2024 non Pribram 1929 "Fusimonas" Kusada et al. 2017 "Gluceribacter" corrig. Kawata et al. 2021 "Ca. Hippenecus" Gilroy et al. 2022 Hoministercoradaptatus Hitch et al. 2022 Howardella Cook et al. 2007 "Ca. Lachnocurva" Holm et al. 2020 "Maccoya" Hitch et al. 2024 "Ca. Merdinaster" Gilroy et al. 2022 "Ca. Minthocola" Gilroy et al. 2022 "Naizhengia" Huang et al. 2024 "Sakamotonia" Hitch et al. 2024 "Sanxizhangella" Huang et al. 2024 Suonthocola Hitch et al. 2022 Sporobacterium Mechichi et al. 1999 Syntrophococcus Krumholz & Bryant 1986 "Weimerbacter" Scarborough et al. 2019 "Yonghella" Huang et al. 2024
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