W110 may refer to:
Art
John the Baptist preaching (W110), a circa 1633/1634 painting by Rembrandt; see List of paintings by Rembrandt.
Electronics
The LG G Watch R, an Android-based smartwatch released in 2014. The Sony Cybershot DSC-W110 camera; see List of Sony Cyber-shot cameras#W series.
Games
Idro, a fantasy wargame published by International Team in 1980, with code W110.
Mathematics
Rule 110, a Turing-complete one-dimensional cellular automaton. The small snub icosicosidodecahedron, Wenninger number W110.
Transportation
The Mercedes-Benz W110, a line of midsize automobiles in the 1960s. The Nissan Bluebird W110/112/113 station wagon, a 1950s automobile; see Nissan Bluebird#110 series.